Malissa was born Dec. 31, 1888, in Breckinridge County, Kentucky, the daughter of Robert and Ellen Powers Mattingly, descendants of the Maryland pioneers who came to Kentucky. From words and example of her parents, Malissa learned the beauty and truths of the Catholic faith. Her school days were spent in the public schools of Breckinridge County. After completing a commercial course, Malissa kept books for a business in Cloverport for a number of years. Religious life appealed to her. She entered the novitiate at Mount Saint Joseph on February 2, 1915. She received the Ursuline habit on August 10 and the name Sister Angeline.
Sister Angeline’s apostolic work of teaching began in 1916 at St. Charles High School ‑‑ a public school in Marion County at St. Mary, Kentucky. In 1920, at the request of the superintendent in Washington County, she opened Holy Trinity High School, a public school in Fredericktown, Kentucky. Over the years, she taught in several other Kentucky schools: Holy Cross, Louisville (St. Columba and St. Paul), Stanley, and Fancy Farm (St. Denis). In 1930, she was missioned for one year at St. Bernard Academy in Nebraska City, Nebraska. From 1933 to 1951, Sister Angeline taught science at Mount Saint Joseph Junior College and Academy. During this time she began night classes in Owensboro for nurses at Daviess County Hospital. She taught in the science department at Brescia College from its beginning until 1955. After leaving Brescia College she taught in Knottsville High School and St. Catherine High School, New Haven, Kentucky.
Due to failing health in 1959, Sister Angeline retired to the Motherhouse infirmary. She became a permanent bed patient in October of 1961, suffering from acute anemia in need of frequent blood transfusions. She died March 2, 1962. On March 5, Msgr. Gilbert Henninger, chaplain, offered the funeral Mass. Sister Angeline’s remains rest in the convent cemetery.